The Role of Hormones in Glucose Homeostasis and Diabetes Treatment

Diabetes mellitus is a very common disorder caused by high levels of sugar in the bloodstream. It is caused by problems with the hormone named insulin and also be affected or precipitated by other hormones. It has long been known that several peptide hormones have significant impact on the regulation of glucose homeostasis. Hormone-based therapies effectively lead to prevent or slow the progression of diabetes. Here we summarize the roles of metabolic hormones such as insulin, GLP-1, leptin, FGF21, adiponectin, ghrelin, nesfatin, etc. in glucose metabolism and therapies of diabetes.